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[经皮腔内冠状动脉成形术。法国心脏病学会心血管功能研究工作组多中心研究结果]

[Transluminal coronary angioplasty. Results of the multicenter study of the Working Group on Functional Cardiovascular Research of the French Society of Cardiology].

作者信息

Marco J

出版信息

Arch Mal Coeur Vaiss. 1983 Apr;76(4):363-9.

PMID:6223607
Abstract

A multicentre study instituted by the "Functional Cardiovascular Investigations" working group of the French Cardiac Society assembled 219 cases files of patients who had undergone attempted transluminal angioplasty for coronary artery stenosis according to Gruntzig's protocol, between August 1979 and October 1981. The stenosis was catheterised in 179 cases (81 p. 100) and a good result was obtained in 152 patients (69 p. 100). One or more complications occurred in 25 patients (11 p. 100) including one death, 16 emergency aortocoronary bypass procedures (7,3 p. 100) and 7 myocardial infarctions (3,2 p. 100). Medium term follow-up of these patients showed an incidence of restenosis of between 16 p. 100 (24 patients with angina out of the 152 primary successes) and 32 p. 100 (25 of the 77 patients controlled by coronary angiography). The results of this multicentre trial are compared to those reported by the National Heart Lung and Blood Institute. We conclude that transluminal coronary angioplasty gives a good result which is maintained (in some patients after 2 dilatations) in 60 p. 100 of cases, with, however, a risk which is not negligeable: the indications for this procedure should therefore be restricted.

摘要

法国心脏病学会“功能性心血管研究”工作组开展的一项多中心研究,收集了1979年8月至1981年10月期间,按照格伦齐格方案接受冠状动脉狭窄经皮腔内血管成形术尝试的219例患者的病历。179例(81%)患者的狭窄部位成功插入导管,152例(69%)患者取得良好效果。25例(11%)患者出现一种或多种并发症,包括1例死亡、16例急诊主动脉冠状动脉搭桥手术(7.3%)和7例心肌梗死(3.2%)。对这些患者的中期随访显示,再狭窄发生率在16%(152例初次成功患者中有24例出现心绞痛)至32%(77例接受冠状动脉造影检查的患者中有25例)之间。将这项多中心试验的结果与美国国立心肺血液研究所报告的结果进行了比较。我们得出结论,经皮腔内冠状动脉成形术效果良好,60%的病例(部分患者在进行2次扩张后)效果得以维持,然而,风险不可忽视:因此,该手术的适应症应予以限制。

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