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[经皮腔内冠状动脉成形术的并发症。一项法国多中心研究(1983年)]

[Complications of transluminal coronary angioplasty. A multicenter French study (1983)].

作者信息

Valeix B, Labrunie P, Marco J, Cherrier F, Cuillière M, Bertrand M, Schmitt R, Sabatier M, Gaspard P, Guermonprez J L

出版信息

Arch Mal Coeur Vaiss. 1985 Mar;78(3):331-8.

PMID:3159367
Abstract

The authors report the complications observed during 1 247 transluminal coronary angioplasties (TCA) performed in 1 187 patients in 17 french centers between 1979 and October 1983. There were 855 primary successes (68.9 p. 100). There were 41 cases of symptomatic dissection (3.3 p. 100) of which 32 underwent aortocoronary bypass surgery with a residual myocardial infarction (MI) in 13 cases (40.6 p. 100). Medical treatment of symptomatic dissection gave very poor results (7 out of 9 MI) and is formally contra-indicated. 67 per- or postoperative occlusions were observed (5.3 p. 100). This is the most serious complication which necessitates an emergency revascularisation procedure (TCA or coronary bypass surgery--CBS--) because MI rapidly follows in patients without a well-developed collateral circulation. In this series MI occurred in 28 out of 45 patients--62 p. 100--despite CBS. This underlines the value of an immediate repeat TCA which, when successful, results in a much faster revascularisation. Seventy-three MI (5.8 p. 100) were observed in the first 24 hours: 50 p. 100 were secondary to an angiographically documented coronary occlusion. The other two causes were coronary dissection and spasm. Emergency CBS was carried out in 107 cases (8.9 p. 100) mainly for coronary occlusion or symptomatic dissection. The mortality was 11 out of 1 187 patients (0.93 p. 100). Death occurred in the catheter laboratory in 3 cases, during the first 24 hours in the operating theatre in 1 case, and after the first 24 hours but before hospital discharge in 7 patients.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

作者报告了1979年至1983年10月期间在法国17个中心对1187例患者进行的1247例经皮腔内冠状动脉成形术(TCA)中观察到的并发症。其中855例初次手术成功(占68.9%)。有41例出现有症状的夹层(占3.3%),其中32例行主动脉冠状动脉搭桥手术,13例(占40.6%)残留心肌梗死(MI)。有症状夹层的药物治疗效果很差(9例中有7例发生MI),且明确为禁忌。观察到67例术中或术后闭塞(占5.3%)。这是最严重的并发症,对于没有完善侧支循环的患者,MI会迅速发生,因此需要紧急血运重建手术(TCA或冠状动脉搭桥手术——CBS)。在本系列中,45例患者中有28例(占62%)尽管接受了CBS仍发生MI。这凸显了立即重复TCA的价值,成功的话能更快实现血运重建。在最初24小时内观察到73例MI(占5.8%):其中50%继发于血管造影记录的冠状动脉闭塞。另外两个原因是冠状动脉夹层和痉挛。107例(占8.9%)主要因冠状动脉闭塞或有症状夹层而进行了紧急CBS。1187例患者中有11例死亡(占0.93%)。3例在导管室死亡,1例在术后24小时内在手术室死亡,7例在术后24小时后但出院前死亡。(摘要截取自250字)

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