大肠杆菌的SOS系统在噬菌体λ发育调控中的作用

The SOS system of Escherichia coli in the regulation of bacteriophage lambda development.

作者信息

Kopylov V M

出版信息

FEBS Lett. 1983 Aug 22;160(1-2):7-10. doi: 10.1016/0014-5793(83)80925-9.

Abstract

A sequence homologous to the known SOS boxes is found in the Po promoter of phage lambda. It is suggested that the sequence found is a binding site for the LexA repressor. The mechanism of the LexA part in regulation of lambda development is discussed. It is based on the competitive transcription of the RNA encoding CII protein and the short OOP-RNA transcribed from the Po promoter.

摘要

在噬菌体λ的Po启动子中发现了一个与已知SOS框同源的序列。有人认为所发现的序列是LexA阻遏物的结合位点。文中讨论了LexA在λ发育调控中的作用机制。它基于编码CII蛋白的RNA与从Po启动子转录的短OOP-RNA的竞争性转录。