Mozziconacci P
Presse Med. 1983 Sep 3;12(30):1863-6.
In this critical nosological study of chronic juvenile rheumatoid arthritis, the author opposes his own pluralist concept based on a longitudinal analysis of the overall development to the conventional unicist concept in which the three forms of the disease are regarded as initial presentations of one single entity. The relationship between the systemic form and the abarticular hyperimmune syndromes previously described by Wissler and Fanconi is stressed. Similarities between juvenile rheumatoid arthritis and reactional inflammatory joint diseases of well defined aetiology are discussed; both are considered articular immune reactions to more or less demonstrable antigens. In the absence of specific laboratory tests, the disease can only be defined on clinical grounds. Without being exceedingly wide, this definition should be less restrictive than that based on currently accepted criteria.
在这项关于慢性青少年类风湿性关节炎的关键疾病分类学研究中，作者基于对整体发展的纵向分析，将自己基于多元论的概念与传统的一元论概念相对立，在传统概念中，该疾病的三种形式被视为单一实体的初始表现。文中强调了全身型与先前由维斯勒和范科尼描述的关节外超免疫综合征之间的关系。讨论了青少年类风湿性关节炎与病因明确的反应性炎症性关节疾病之间的相似之处；两者都被认为是对或多或少可证实的抗原的关节免疫反应。在缺乏特异性实验室检查的情况下，该疾病只能根据临床依据来定义。这个定义虽然不会过于宽泛，但应该比基于目前公认标准的定义限制更少。
