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Ceftazidime in patients with Pseudomonas infections.

作者信息

Eron L J, Park C H, Hixon D L, Goldenberg R I, Poretz D M

出版信息

J Antimicrob Chemother. 1983 Jul;12 Suppl A:161-9. doi: 10.1093/jac/12.suppl_a.161.

DOI:10.1093/jac/12.suppl_a.161
PMID:6225762
Abstract

Ceftazidime was administered to 41 patients with serious infections caused by Pseudomonas aeruginosa (24 cases) and other bacteria (17 cases). The clinical response rate of pseudomonas infections (88%) was similar to that of other bacteria (94%) with microbiological eradication of 83% of initial pseudomonas isolates compared to 82% of non-pseudomonas strains. The development of resistance to ceftazidime during therapy was observed in 3 cases (Enterobacter agglomerans, Enterobacter cloacae, and Ps. aeruginosa), and superinfection by a resistant Enterobacter agglomerans occurred in one case. Adverse reactions of clinical significance included two cases of leukopenia and one case each of azotaemia, diarrhoea (Clostridium difficile toxin positive), and rash.

摘要

相似文献

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Ceftazidime in patients with Pseudomonas infections.
J Antimicrob Chemother. 1983 Jul;12 Suppl A:161-9. doi: 10.1093/jac/12.suppl_a.161.
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