Mills O H, Kligman A M
Dermatologica. 1983;167(2):57-63. doi: 10.1159/000249749.
The 'follicular biopsy' is an extension of the noninvasive 'surface biopsy' technique originated by Dawber and Marks. A quick-setting cyanoacrylate polymer is used to extract the contents of sebaceous follicles. The retrieved material can be examined histologically at the light or electron microscopic level. Many types of analyses may be performed; microbial density, lipid components (acne), mite population (Demodex), hair retention (trichostasis), penetration of topical drugs and chemicals, localization of enzymes, etc. The follicular biopsy is useful for studying the contents of sebaceous follicles in health and disease.
“毛囊活检”是由道伯（Dawber）和马克斯（Marks）首创的非侵入性“表面活检”技术的延伸。一种速凝氰基丙烯酸酯聚合物用于提取皮脂腺毛囊的内容物。所获取的材料可在光学或电子显微镜水平进行组织学检查。可以进行多种类型的分析，如微生物密度、脂质成分（痤疮）、螨虫数量（蠕形螨）、毛发滞留（毛发角质化）、局部药物和化学物质的渗透、酶的定位等。毛囊活检对于研究健康和疾病状态下皮脂腺毛囊的内容物很有用。
