Goodyer P R, Fong J S, Kaplan B S
Am J Nephrol. 1982;2(5):272-5. doi: 10.1159/000166660.
An adolescent girl with short stature and learning disability was found to have an unusual variant of Turner's syndrome, 46X, del (X) (p 11) and an abnormal urinary sediment. Further studies demonstrated persistent depression of C3 and histologic evidence of membranoproliferative glomerulonephritis (MPGN). The occurrence of MPGN in this case may have been a manifestation of the known tendency for Turner patients to develop immunologic disease.
一名身材矮小且有学习障碍的青春期女孩被发现患有特纳综合征的一种罕见变异型,即46,X,del(X)(p11),同时伴有异常的尿沉渣。进一步研究显示C3持续降低,并有膜增生性肾小球肾炎(MPGN)的组织学证据。该病例中MPGN的发生可能是特纳综合征患者已知的发生免疫性疾病倾向的一种表现。