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不同鱼腥藻菌株中铁载体介导的铁吸收

Siderophore-mediated iron uptake in different strains of Anabaena sp.

作者信息

Goldman S J, Lammers P J, Berman M S, Sanders-Loehr J

出版信息

J Bacteriol. 1983 Dec;156(3):1144-50. doi: 10.1128/jb.156.3.1144-1150.1983.

DOI:10.1128/jb.156.3.1144-1150.1983
PMID:6227608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217960/
Abstract

Anabaena sp. strain 6411, which produces the dihydroxamate siderophore schizokinen to facilitate iron uptake, is also capable of using the related siderophore aerobactin. The two siderophores compete for the same iron transport system, but there is a markedly higher affinity for ferric schizokinen than for ferric aerobactin. The trihydroxamate siderophore ferrioxamine B is far less effective as an iron donor in this organism. Anabaena sp. strain 7120 appears to be closely related to strain 6411. It synthesizes schizokinen as its major siderophore and shows rates of iron uptake from ferric schizokinen, ferric aerobactin, and ferrioxamine B which are similar to those observed with strain 6411. Anabaena cylindrica Lemm. 7122 and 1611, on the other hand, differ from strain 6411. In contrast to schizokinen, the hydroxamate which they produce in response to iron starvation cannot be extracted with water from the organic layer and does not support the growth of the siderophore auxotroph Arthrobacter flavescens JG-9. Strain 7122 can use its endogenous siderophore or schizokinen to promote iron uptake, but at 50-fold-lower rates than are observed with Anabaena sp. strain 6411 or 7120.

摘要

鱼腥藻属6411菌株可产生二异羟肟酸型铁载体裂殖藻素以促进铁的吸收,它也能够利用相关铁载体气杆菌素。这两种铁载体竞争同一铁转运系统,但对裂殖藻素铁的亲和力明显高于对气杆菌素铁的亲和力。三异羟肟酸型铁载体去铁胺B在该生物体中作为铁供体的效果要差得多。鱼腥藻属7120菌株似乎与6411菌株密切相关。它合成裂殖藻素作为其主要铁载体,并且从裂殖藻素铁、气杆菌素铁和去铁胺B吸收铁的速率与在6411菌株中观察到的相似。另一方面,圆柱鱼腥藻Lemm. 7122和1611与6411菌株不同。与裂殖藻素不同,它们在缺铁时产生的异羟肟酸不能用水从有机层中提取出来,也不能支持铁载体营养缺陷型黄色节杆菌JG-9的生长。7122菌株可以利用其内源铁载体或裂殖藻素来促进铁的吸收,但速率比在鱼腥藻属6411菌株或7120菌株中观察到的低50倍。

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本文引用的文献

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Isolation of the siderophore schizokinen from soil of rice fields.从稻田土壤中分离出铁载体希洛可宁。
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Active transport of ferric schizokinen in Anabaena sp.鱼腥藻中裂殖素铁的主动运输
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Hydroxamate recognition during iron transport from hydroxamate-ion chelates.从异羟肟酸离子螯合物进行铁转运过程中的异羟肟酸识别。
J Bacteriol. 1973 Sep;115(3):912-8. doi: 10.1128/jb.115.3.912-918.1973.
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Blue-green algae: their excretion of iron-selective chelators enables them to dominate other algae.蓝绿藻:它们分泌的铁选择性螯合剂使它们能够在其他藻类中占据主导地位。
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