Saha K, Mittal M M, Maheswari H B
Vox Sang. 1978;34(2):104-10. doi: 10.1111/j.1423-0410.1978.tb03731.x.
An attempt was made to repair cell-mediated immunity in 7 patients suffering from lepromatous leprosy and severe erythema nodosum leprosum by intravenous infusion of 400 million allogeneic blood lymphocytes on 3 occasions. The lymphocytes were obtained from lepromin and tuberculin-positive subjects and were inactivated in vitro by treatment with mitomycin C. Immunotherapy with inactivated lymphocytes only modified the severity of erythema nodosum leprosum, without altering other aspects of the disease.
尝试通过三次静脉输注4亿个同种异体血淋巴细胞，对7例瘤型麻风及严重麻风结节性红斑患者的细胞介导免疫进行修复。淋巴细胞取自麻风菌素和结核菌素呈阳性的受试者，并在体外经丝裂霉素C处理使其失活。用失活淋巴细胞进行免疫治疗仅改变了麻风结节性红斑的严重程度，而未改变疾病的其他方面。
