Baron J C, Bousser M G, Comar D, Rougemont D, Lebrun-Grandié P, Castaigne P
Presse Med. 1983 Dec 29;12(48):3066-72.
The development of positron emission tomography now allows the local study of cerebral blood flow, oxygen consumption and glucose utilization in ischemic stroke patients. In recent cerebral infarction, a disruption of the normal couple between flow and metabolism is almost constantly observed: in the first few days cerebral blood flow is either inadequate (persistent ischemia) or over-abundant ("luxury perfusion"), whereas a late "luxury perfusion" is almost constant within the necrotic area between the 10th and the 40th day. Threshold values for cerebral blood flow and oxygen consumption that are ultimately associated with necrosis or tissue integrity have been determined. A metabolic depression without C.T. Scan counterpart has been observed in various brain structures remote from the infarcted area per se. Lastly, the hemodynamic and metabolic effects the superficial-temporal-middle-cerebral-artery anastomosis have been studied.
正电子发射断层扫描技术的发展，现在能够对缺血性中风患者的脑血流量、氧耗量和葡萄糖利用率进行局部研究。在近期发生的脑梗死中，几乎总能观察到血流与代谢之间正常耦合关系的破坏：在最初几天，脑血流量要么不足（持续性缺血），要么过多（“奢侈灌注”），而在第10天至第40天之间，坏死区域内后期的“奢侈灌注”几乎是持续存在的。已经确定了最终与坏死或组织完整性相关的脑血流量和氧耗量阈值。在远离梗死区域本身的各种脑结构中，观察到了一种没有CT扫描对应表现的代谢抑制现象。最后，还对颞浅-大脑中动脉吻合术的血流动力学和代谢效应进行了研究。
