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[雄性阿拉伯狒狒血液中雄激素水平的昼夜节律]

[Circadian rhythms of androgen levels in the blood of male hamadryas baboons].

作者信息

Taranov A G, Goncharov N P

出版信息

Biull Eksp Biol Med. 1984 Jan;97(1):89-91.

PMID:6229295
Abstract

Radioimmunoassay was used to investigate circadian rhythms of blood plasma testosterone, 5 alpha-dihydrotestosterone, androstendione and dehydroepiandrosterone in intact animals and in those preadapted for experimental conditions. Blood plasma of monkey demonstrated monophasic circadian rhythms in the levels of androstendione, dehydroepiandrosterone and 5 alpha-dihydrotestosterone, with the maximal values seen early in the morning and minimal values in the evening. Circadian rhythms of testosterone were opposite in character. The adaptation of monkeys for housing and experimental conditions was marked by an increase in testosterone and 5 alpha-dihydrotestosterone levels in the blood as well as by an insignificant elevation of the levels of androgens of adrenal origin, leading to the changes in circadian rhythms of steroid hormones.

摘要

采用放射免疫分析法研究了完整动物及预先适应实验条件的动物血浆睾酮、5α-双氢睾酮、雄烯二酮和脱氢表雄酮的昼夜节律。猴子血浆中,雄烯二酮、脱氢表雄酮和5α-双氢睾酮水平呈现单相昼夜节律,清晨达到最大值,傍晚达到最小值。睾酮的昼夜节律则相反。猴子适应饲养和实验条件的表现为血液中睾酮和5α-双氢睾酮水平升高,以及肾上腺源性雄激素水平略有升高,从而导致甾体激素昼夜节律发生变化。

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