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[阿拉伯狒狒血液中皮质类固醇及其前体浓度的昼夜节律与垂体 - 肾上腺皮质系统初始功能状态之间的关系特征]

[Characteristics of the relationship between the circadian rhythm of the concentrations of corticosteroids and their precursors in the blood of baboon hamadryas and the initial functional state of the pituitary-adrenal cortex system].

作者信息

Taranov A G, Goncharov N P

出版信息

Biull Eksp Biol Med. 1981 Feb;91(2):219-22.

PMID:7225562
Abstract

The occurrence of a single-phase circadian rhythm in the content of cortisole, 11-deoxycortisole, 17-hydroxypregnenolone, 17-hydroxyprogesterone, pregnenolone and progesterone in the blood plasma of hamadryas baboons was established by radioimmunoassay with peak levels early in the morning and minimum ones in the evening. The time course of changes in aldosterone levels in the intact animals significantly differs from that in the adapted ones. The maintenance of animals under other ecological conditions results in the decreased levels of all steroids studied and in significant changes in circadian rhythms of the content of cortisol precursors.

摘要

通过放射免疫测定法确定了阿拉伯狒狒血浆中皮质醇、11-脱氧皮质醇、17-羟孕烯醇酮、17-羟孕酮、孕烯醇酮和孕酮含量的单相昼夜节律,其峰值出现在清晨,最低值出现在傍晚。完整动物体内醛固酮水平的变化时间进程与适应动物的明显不同。在其他生态条件下饲养动物会导致所有研究类固醇的水平降低,以及皮质醇前体含量昼夜节律的显著变化。

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