Kopf A, Boue F, Delfraissy J F, Charton M, Brisset J M, Duclos J M, Galanaud P
Presse Med. 1984 Jan 21;13(2):83-6.
Eosinophilic cystitis, of which 35 cases have been published, is a recurrent cystitis remarkable for its chronicity and for the importance of haematuria; the urine is usually sterile and blood eosinophilia frequently present; at histology, infiltration of the vesical wall by eosinophils is pathognomonic. In view of the irregular results of cortico-steroid treatment, a search for causative factors is required. Parasitic infestation has been suspected but never actually proven, and an allergic origin probably is frequently missed. We report two cases of eosinophilic cystitis where allergy to penicillin and clometacin respectively could be demonstrated for the first time and in which the condition subsided after withdrawal of these drugs.
嗜酸性膀胱炎已报道35例，是一种复发性膀胱炎，以其慢性病程和血尿的重要性为显著特点；尿液通常无菌，常伴有血液嗜酸性粒细胞增多；组织学上，膀胱壁嗜酸性粒细胞浸润具有诊断意义。鉴于皮质类固醇治疗结果不规律，需要寻找致病因素。曾怀疑有寄生虫感染但从未得到实际证实，而且可能经常漏诊过敏起源。我们报告两例嗜酸性膀胱炎，首次证实分别对青霉素和氯灭酸过敏，停用这些药物后病情缓解。
