Clark H B, Schmidt R E
Brain Res. 1984 Feb 20;293(2):390-5. doi: 10.1016/0006-8993(84)91250-2.
Markedly dilated dystrophic post-ganglionic sympathetic axons have been identified by dopamine-beta-hydroxylase immunohistochemistry in the paravascular ileal mesenteric nerves of rats with chronic streptozotocin diabetes. Many axons contained multiple dilatations with interposed axonal segments of near normal dimensions. These axonal abnormalities were absent in control animals. The time course of the development of the axonopathy and its distribution in the alimentary tract correlate with quantitative ultrastructural findings previously reported in this system.
通过多巴胺-β-羟化酶免疫组织化学方法，在患有慢性链脲佐菌素糖尿病的大鼠回肠肠系膜血管旁神经中，已鉴定出明显扩张的营养不良性节后交感神经轴突。许多轴突含有多个扩张部位，其间夹杂着尺寸接近正常的轴突节段。对照动物中不存在这些轴突异常。轴突病的发展时间进程及其在消化道中的分布与先前在该系统中报道的定量超微结构研究结果相关。
