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[下丘脑结构在异相睡眠吲哚胺能机制中的作用]

[Implication of hypothalamic structures in indolaminergic mechanisms of paradoxical sleep].

作者信息

Sallanon M, Petitjean F, Buda C, Janin M, Jouvet M

出版信息

C R Seances Acad Sci III. 1983;297(11):531-4.

PMID:6230141
Abstract

Intratissue injection of 1 to 20 micrograms of L-5 HTP in numerous areas of the cat brainstem failed to reverse P-chlorophenylalanine induced insomnia. On the other hand, injection of 2 to 7 micrograms of L-5 HTP in the ventrolateral hypothalamus induced both slow wave sleep and paradoxical sleep after 36 and 76 min.

摘要

在猫脑干的多个区域进行组织内注射1至20微克的L-5羟色氨酸，未能逆转对氯苯丙氨酸诱导的失眠。另一方面，在腹外侧下丘脑注射2至7微克的L-5羟色氨酸，在36分钟和76分钟后诱导出慢波睡眠和异相睡眠。

相似文献

1
[Implication of hypothalamic structures in indolaminergic mechanisms of paradoxical sleep].[下丘脑结构在异相睡眠吲哚胺能机制中的作用]
C R Seances Acad Sci III. 1983;297(11):531-4.
2
[Insomnia induced by P-chlorophenylalanine in cats. Its reversibility by intraventricular injections of indolamines].[对氯苯丙氨酸诱导猫失眠。脑室内注射吲哚胺可逆转这种失眠]
C R Seances Acad Sci D. 1980 Dec 15;291(13):1063-6.
3
[Insomnia induced by p-chlorophenylalanine in the cat. Its reversibility by the intraventricular injection of cerebrospinal fluid taken from cats deprived of paradoxical sleep].[对氯苯丙氨酸诱导猫失眠。通过脑室内注射取自剥夺异相睡眠的猫的脑脊液可使其恢复正常]
C R Seances Acad Sci III. 1981 Jan 5;292(1):113-7.
4
Reversibility of para-chlorophenylalanine-induced insomnia by intrahypothalamic microinjection of L-5-hydroxytryptophan.通过下丘脑内微量注射L-5-羟色氨酸逆转对氯苯丙氨酸诱导的失眠
Neuroscience. 1989;28(1):83-94. doi: 10.1016/0306-4522(89)90234-0.
5
Increase of paradoxical sleep induced by microinjections of ibotenic acid into the ventrolateral part of the posterior hypothalamus in the cat.向猫的下丘脑后部腹外侧部分微量注射鹅膏蕈氨酸引起异相睡眠增加。
Arch Ital Biol. 1988 Feb;126(2):87-97.
6
[Insomnia caused by administration of para-chlorophenylalanine: reversibility by peripheral or central injection of 5-hydroxytryptophan and serotonin].[对氯苯丙氨酸给药所致失眠：外周或中枢注射5-羟色氨酸和血清素的可逆性]
Sleep. 1985;8(1):56-67.
7
5-HT antagonists suppress sleep and delay its restoration after 5-HTP in p-chlorophenylalanine-pretreated cats.5-羟色胺拮抗剂可抑制对氯苯丙氨酸预处理猫的睡眠，并在给予5-羟色胺酸后延迟其睡眠恢复。
Eur J Pharmacol. 1982 Aug 13;82(1-2):29-35. doi: 10.1016/0014-2999(82)90549-0.
8
[Specific neurons for wakefulness in the posterior hypothalamus in the cat].[猫下丘脑后部中负责清醒的特定神经元]
C R Acad Sci III. 1984;298(7):195-200.
9
Influence of hypnogenic brain areas on wakefulness- and rapid-eye-movement sleep-related neurons in the brainstem of freely moving cats.催眠脑区对自由活动猫脑干中与觉醒及快速眼动睡眠相关神经元的影响。
J Neurosci Res. 2004 Jan 1;75(1):133-42. doi: 10.1002/jnr.10827.
10
[Effect of partial deprivation of slow-wave sleep on the structure of the sleep-wakefulness cycle].[慢波睡眠部分剥夺对睡眠-觉醒周期结构的影响]
Fiziol Zh SSSR Im I M Sechenova. 1984 Aug;70(8):1142-8.

引用本文的文献

1
The role of 5-hydroxytryptophan (5-HTP) in the regulation of the sleep/wake cycle in parachlorophenylalanine (p-CPA) pretreated rat: a multiple approach study.5-羟色氨酸（5-HTP）在对氯苯丙氨酸（p-CPA）预处理大鼠睡眠/觉醒周期调节中的作用：一项多方法研究
Exp Brain Res. 1991;86(1):117-24. doi: 10.1007/BF00231046.