Evatt B L, Ramsey R B, Lawrence D N, Zyla L D, Curran J W
Ann Intern Med. 1984 Apr;100(4):499-504. doi: 10.7326/0003-4819-100-4-499.
Since mid-1981 the Centers for Disease Control (CDC) has received reports of more than 1900 cases of the acquired immunodeficiency syndrome. These cases had either Kaposi's sarcoma confirmed by biopsy or a life-threatening opportunistic infection confirmed by biopsy or culture. In January 1982 a hemophiliac with Pneumocystis carinii pneumonia was reported to the CDC, and by July 1982 two other hemophiliacs had developed P. carinii pneumonia. During the next 12 months a total of 22 confirmed cases of the acquired immunodeficiency syndrome occurred in hemophiliacs, 17 in the United States and 5 outside the United States. We report the nature of the epidemic of the acquired immunodeficiency syndrome in hemophiliacs and summarize pertinent clinical aspects.
自1981年年中以来,疾病控制中心(CDC)已收到1900多例获得性免疫缺陷综合征的报告。这些病例要么经活检确诊为卡波西肉瘤,要么经活检或培养确诊为危及生命的机会性感染。1982年1月,一名患有卡氏肺孢子虫肺炎的血友病患者被报告给疾病控制中心,到1982年7月,另外两名血友病患者也患上了卡氏肺孢子虫肺炎。在接下来的12个月里,血友病患者中总共出现了22例确诊的获得性免疫缺陷综合征病例,其中17例在美国,5例在美国境外。我们报告了血友病患者中获得性免疫缺陷综合征的流行情况,并总结了相关的临床方面。