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血友病患者的获得性免疫缺陷综合征

The acquired immunodeficiency syndrome in patients with hemophilia.

作者信息

Evatt B L, Ramsey R B, Lawrence D N, Zyla L D, Curran J W

出版信息

Ann Intern Med. 1984 Apr;100(4):499-504. doi: 10.7326/0003-4819-100-4-499.

DOI:10.7326/0003-4819-100-4-499
PMID:6230977
Abstract

Since mid-1981 the Centers for Disease Control (CDC) has received reports of more than 1900 cases of the acquired immunodeficiency syndrome. These cases had either Kaposi's sarcoma confirmed by biopsy or a life-threatening opportunistic infection confirmed by biopsy or culture. In January 1982 a hemophiliac with Pneumocystis carinii pneumonia was reported to the CDC, and by July 1982 two other hemophiliacs had developed P. carinii pneumonia. During the next 12 months a total of 22 confirmed cases of the acquired immunodeficiency syndrome occurred in hemophiliacs, 17 in the United States and 5 outside the United States. We report the nature of the epidemic of the acquired immunodeficiency syndrome in hemophiliacs and summarize pertinent clinical aspects.

摘要

自1981年年中以来,疾病控制中心(CDC)已收到1900多例获得性免疫缺陷综合征的报告。这些病例要么经活检确诊为卡波西肉瘤,要么经活检或培养确诊为危及生命的机会性感染。1982年1月,一名患有卡氏肺孢子虫肺炎的血友病患者被报告给疾病控制中心,到1982年7月,另外两名血友病患者也患上了卡氏肺孢子虫肺炎。在接下来的12个月里,血友病患者中总共出现了22例确诊的获得性免疫缺陷综合征病例,其中17例在美国,5例在美国境外。我们报告了血友病患者中获得性免疫缺陷综合征的流行情况,并总结了相关的临床方面。

相似文献

1
The acquired immunodeficiency syndrome in patients with hemophilia.血友病患者的获得性免疫缺陷综合征
Ann Intern Med. 1984 Apr;100(4):499-504. doi: 10.7326/0003-4819-100-4-499.
2
[Acquired immunodeficiency syndrome and related syndromes in hemophiliacs: status throughout the world].[血友病患者的获得性免疫缺陷综合征及相关综合征:全球现状]
Rev Fr Transfus Immunohematol. 1984 Sep;27(4):493-6. doi: 10.1016/s0338-4535(84)80147-6.
3
[Hemophilia and HTLV-III infection].
Z Hautkr. 1986 Dec 1;61(23):1687-704.
4
Occurrence of AIDS in hemophiliacs in Japan.
Semin Thromb Hemost. 1985 Oct;11(4):352-6. doi: 10.1055/s-2007-1004393.
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Epidemiology of the acquired immunodeficiency syndrome (AIDS).获得性免疫缺陷综合征(艾滋病)的流行病学
Epidemiol Rev. 1985;7:1-21. doi: 10.1093/oxfordjournals.epirev.a036277.
6
Pneumocystis carinii pneumonia (PCP) in a hemophiliac with transfusion-acquired AIDS.一名因输血感染艾滋病的血友病患者发生卡氏肺孢子虫肺炎(PCP)
Semin Roentgenol. 1987 Jul;22(3):146-9. doi: 10.1016/0037-198x(87)90027-7.
7
Acquired immune deficiency syndrome in the United States: the first 1,000 cases.美国的获得性免疫缺陷综合征:首批1000例病例
J Infect Dis. 1983 Aug;148(2):339-45. doi: 10.1093/infdis/148.2.339.
8
AIDS in hemophilia.血友病患者中的艾滋病
Ann N Y Acad Sci. 1984;437:466-71. doi: 10.1111/j.1749-6632.1984.tb37169.x.
9
Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?艾滋病患者中的卡波西肉瘤:一种性传播感染?
Lancet. 1990 Jan 20;335(8682):123-8. doi: 10.1016/0140-6736(90)90001-l.
10
Acquired immunodeficiency syndrome among patients attending hemophilia treatment centers and mortality experience of hemophiliacs in the United States.美国血友病治疗中心患者中的获得性免疫缺陷综合征及血友病患者的死亡情况
Am J Epidemiol. 1985 Jun;121(6):797-810. doi: 10.1093/oxfordjournals.aje.a114051.

引用本文的文献

1
Pathogenesis of human immunodeficiency virus infection.人类免疫缺陷病毒感染的发病机制
Microbiol Rev. 1993 Mar;57(1):183-289. doi: 10.1128/mr.57.1.183-289.1993.
2
Foreign-protein-mediated immunodeficiency in hemophiliacs with and without HIV.有和没有感染HIV的血友病患者中由外源蛋白介导的免疫缺陷
Genetica. 1995;95(1-3):51-70. doi: 10.1007/BF01435001.
3
Unresponsiveness to skin testing with bacterial antigens in patients with haemophilia A not apparently infected with human immunodeficiency virus (HIV).在未明显感染人类免疫缺陷病毒(HIV)的甲型血友病患者中,对细菌抗原皮肤试验无反应。
J Clin Pathol. 1987 Aug;40(8):849-52. doi: 10.1136/jcp.40.8.849.
4
Factor VIII concentrate for hemophilia: comparison of two heat-treated products.用于血友病的凝血因子 VIII 浓缩剂:两种热处理产品的比较。
CMAJ. 1987 Jan 15;136(2):150-2.
5
AIDS and haemophilia: morbidity and morality in a well defined population.艾滋病与血友病:特定人群中的发病率与死亡率
Br Med J (Clin Res Ed). 1985 Sep 14;291(6497):695-9. doi: 10.1136/bmj.291.6497.695.
6
Seroconversion of human T cell lymphotrophic virus III (HTLV-III) in patients with haemophilia: a longitudinal study.血友病患者中人类嗜T淋巴细胞病毒III型(HTLV-III)的血清转化:一项纵向研究。
Br Med J (Clin Res Ed). 1985 Jun 8;290(6483):1705-6. doi: 10.1136/bmj.290.6483.1705-a.
7
Neuropathology of HIV infection in haemophiliacs: comparative necropsy study.血友病患者HIV感染的神经病理学:对比尸检研究
BMJ. 1989 Nov 25;299(6711):1312-5. doi: 10.1136/bmj.299.6711.1312.
8
Multiple-dose pharmacokinetics of oral zidovudine in hemophilia patients with human immunodeficiency virus infection.口服齐多夫定在感染人类免疫缺陷病毒的血友病患者中的多剂量药代动力学。
Antimicrob Agents Chemother. 1990 Mar;34(3):394-7. doi: 10.1128/AAC.34.3.394.
9
Intravenous and oral zidovudine pharmacokinetics and coagulation effects in asymptomatic human immunodeficiency virus-infected hemophilia patients.无症状人类免疫缺陷病毒感染的血友病患者静脉注射和口服齐多夫定的药代动力学及凝血作用
Antimicrob Agents Chemother. 1992 Oct;36(10):2245-52. doi: 10.1128/AAC.36.10.2245.