Immune complex diseases (ICD) include different diseases of infectious and noninfectious origin in the pathogenesis of which the leading role belongs to immune complexes circulating in the blood stream. Three variants of the ICD course are distinguished: fulminant, acute, and chronic. The main morphological manifestation of ICD is vasculitis (in the fulminant course--microangiothrombopathy) and its consequences in the form of various circulation disorders. Renal glomeruli are frequently involved (glomerulonephritis). Immunopathologic reactions in the form of hypersensitivity reaction or inhibition of immune response are important in ICD.
免疫复合物疾病(ICD)包括感染性和非感染性起源的不同疾病,其发病机制中起主导作用的是血液循环中的免疫复合物。ICD病程可分为三种类型:暴发性、急性和慢性。ICD的主要形态学表现是血管炎(暴发性病程中为微血管血栓形成)及其导致的各种循环障碍。肾小球常受累(肾小球肾炎)。以超敏反应或免疫反应抑制形式出现的免疫病理反应在ICD中很重要。