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阿司匹林对血管成形术部位血小板沉积的抑制作用:通过血小板闪烁显像证实

Aspirin inhibition of platelet deposition at angioplasty sites: demonstration by platelet scintigraphy.

作者信息

Cunningham D A, Kumar B, Siegel B A, Gilula L A, Totty W G, Welch M J

出版信息

Radiology. 1984 May;151(2):487-90. doi: 10.1148/radiology.151.2.6231656.

DOI:10.1148/radiology.151.2.6231656
PMID:6231656
Abstract

In-111 platelet scintigraphy was used to evaluate the effects of prior aspirin administration on the accumulation of In-111-labeled autologous platelets at sites of arterial injury resulting from iliac, femoral, or popliteal transluminal angioplasty in a nonrandomized study of 17 men. The degree of platelet localization at angioplasty sites was significantly less in nine men who had received aspirin in varying doses within the 4 days before angioplasty than in eight men who had not received aspirin for at least two weeks. Our results suggest that aspirin treatment before angioplasty limits the early platelet deposition at the angioplasty site in men.

摘要

在一项针对17名男性的非随机研究中,铟-111血小板闪烁显像术被用于评估预先服用阿司匹林对因髂动脉、股动脉或腘动脉腔内血管成形术导致的动脉损伤部位铟-111标记的自体血小板聚集的影响。在血管成形术前4天内接受不同剂量阿司匹林治疗的9名男性中,血管成形术部位的血小板定位程度明显低于至少两周未服用阿司匹林的8名男性。我们的研究结果表明,血管成形术前进行阿司匹林治疗可限制男性血管成形术部位早期血小板的沉积。

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1
Aspirin inhibition of platelet deposition at angioplasty sites: demonstration by platelet scintigraphy.阿司匹林对血管成形术部位血小板沉积的抑制作用:通过血小板闪烁显像证实
Radiology. 1984 May;151(2):487-90. doi: 10.1148/radiology.151.2.6231656.
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Deep arterial injury during experimental angioplasty: relation to a positive indium-111-labeled platelet scintigram, quantitative platelet deposition and mural thrombosis.
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Restenosis following percutaneous transluminal angioplasty: clinical, physiologic and pathological features.经皮腔内血管成形术后再狭窄:临床、生理及病理特征
CMAJ. 1986 May 15;134(10):1129-32.
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Late hemodynamic failure following percutaneous transluminal angioplasty for long and multifocal femoropopliteal stenoses.
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