激素水平作为早期先兆流产的预后指标
Hormonal profile as a prognostic index of early threatened abortion.
作者信息
Jovanovic L, Dawood M Y, Landesman R, Saxena B B
出版信息
Am J Obstet Gynecol. 1978 Feb 1;130(3):274-8.
Twelve pregnancies, in which the initial serum hCG titer as measured by RRA was subnormal, were studied to determine if a hormonal profile would serve as a prognostic index of spontaneous abortion. Three of the 12 patients delivered term babies. The hCG titers remained subnormal throughout the pregnancy, however, the serum E2, P, 17alpha-OHP, and PRL remained normal. One of the 12 patients aborted in week 25 of gestation. The serum hCG and PRL were subnormal; however, the serum E2, P, and 17alpha-OHP were normal. Eight of the 12 patients aborted prior to 100 days' gestation. The serum hCG, E2, and PRL were subnormal whereas the P and 17alpha-OHP were normal. Therefore, in patients who have subnormal serum hCG titers, serum E2 and PRL may provide a prognostic index of spontaneous abortion.
对12例初次用放射免疫分析法（RRA）测定血清人绒毛膜促性腺激素（hCG）滴度低于正常的妊娠进行了研究，以确定激素谱是否可作为自然流产的预后指标。12例患者中有3例足月分娩。整个孕期hCG滴度均低于正常，然而，血清雌二醇（E2）、孕酮（P）、17α-羟孕酮（17α-OHP）和催乳素（PRL）均正常。12例患者中有1例在妊娠25周时流产。血清hCG和PRL低于正常；然而，血清E2、P和17α-OHP正常。12例患者中有8例在妊娠100天前流产。血清hCG、E2和PRL低于正常，而P和17α-OHP正常。因此，对于血清hCG滴度低于正常的患者，血清E2和PRL可能提供自然流产的预后指标。
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