去窦主动脉大鼠的心室肥厚
Ventricular hypertrophy in sinoaortic denervated rats.
作者信息
Cabral A M, Vásquez E C, Mill J G, Futuro-Neto H A
出版信息
Braz J Med Biol Res. 1983 Dec;16(4):353-6.
Sinoaortic denervation (SAD) induced a significant increase in mean arterial pressure in male (122 +/- 3 mmHg) and female (126 +/- 3 mmHg) rats compared to male (103 +/- 2 mmHg) and female (106 +/- 3 mmHg) sham-operated (SO) controls (P less than 0.05). A significant increase of the weight of the left ventricle (LV) (11.5%, P less than 0.001) was observed 15 days after surgery in male, but not in female, SAD hypertensive rats compared to pair-fed SO controls. The data suggest that hormonal factors contribute to rapid LV hypertrophy in male SAD hypertensive rats.
与雄性（103±2 mmHg）和雌性（106±3 mmHg）假手术（SO）对照组相比，去主动脉窦神经支配（SAD）使雄性（122±3 mmHg）和雌性（126±3 mmHg）大鼠的平均动脉压显著升高（P<0.05）。与配对喂养的SO对照组相比，雄性SAD高血压大鼠术后15天左心室（LV）重量显著增加（11.5%，P<0.001），而雌性则未出现这种情况。数据表明，激素因素促成了雄性SAD高血压大鼠的快速左心室肥厚。
Zotero 插件