Podugol'nikova O A, Bliumina M G
Genetika. 1982 Dec;18(12):2052-4.
Some reduction of the length of C segments and their variability in chromosomes 1, 9, 16 and Y was exhibited by children having disturbances at an early stage of embryogenesis. The data obtained might suggest a certain activity of the heterochromatic regions during the embryo development. Based on these data, one may also suppose that reduction of the heterochromatin amount may affect the normal morphogenetic processes.
在胚胎发育早期出现发育障碍的儿童,其1号、9号、16号染色体以及Y染色体的C片段长度有所缩短,且变异性降低。所获得的数据可能表明异染色质区域在胚胎发育过程中具有一定活性。基于这些数据,还可以推测异染色质数量的减少可能会影响正常的形态发生过程。