Andò S, Rubens R, Rottiers R
J Endocrinol Invest. 1984 Feb;7(1):21-4. doi: 10.1007/BF03348370.
Plasma level of androgens were studied in 47 normal male controls (20-50 yr-old; mean age 38 yr) and in a group of forty-one male diabetics (23-55 yr-old; mean age: 37.5 yr). Of these 36 showed type II and 5 type I diabetes. The results showed that while the mean basal plasma LH was unchanged, there was a decrease in testosterone levels in the diabetics. Moreover, testosterone binding globulin (TeBG) capacity appeared to be augmented and, as a consequence, the apparent free testosterone concentration (AFTC) was markedly decreased. It is interesting to note that the anomalies in androgen secretion observed are rather similar to those found in elderly man and could play some role (with other factors) in the onset of the frequent sexual disturbances in male diabetics.
对47名正常男性对照组（年龄20 - 50岁；平均年龄38岁）和41名男性糖尿病患者（年龄23 - 55岁；平均年龄：37.5岁）的雄激素血浆水平进行了研究。其中36人患有II型糖尿病，5人患有I型糖尿病。结果显示，虽然基础血浆促黄体生成素（LH）的平均值未发生变化，但糖尿病患者的睾酮水平有所下降。此外，睾酮结合球蛋白（TeBG）的能力似乎增强，因此，表观游离睾酮浓度（AFTC）显著降低。值得注意的是，观察到的雄激素分泌异常与老年男性中发现的异常相当相似，并且（与其他因素一起）可能在男性糖尿病患者频繁出现的性功能障碍的发病中起一定作用。
