Göhlich G, Kuhn W, Höhn H, Przuntek H
J Neurol. 1984;231(1):50-1. doi: 10.1007/BF00313653.
GABA synthesis in skin fibroblasts from patients with Huntington's chorea was compared with that in a control group by means of the highly specific 3H-muscimol radioreceptor assay. A significantly increased rate of GABA synthesis was found in the group with Huntington's chorea in an early cell passage. The possible use of this method for early diagnosis of Huntington's chorea is considered.
通过高特异性的3H-蝇蕈醇放射受体分析法，比较了亨廷顿舞蹈症患者皮肤成纤维细胞中的γ-氨基丁酸（GABA）合成与对照组中的情况。在早期细胞传代时，发现亨廷顿舞蹈症组的GABA合成速率显著增加。考虑了该方法在亨廷顿舞蹈症早期诊断中的可能应用。
