皮肤淋巴瘤样肉芽肿病：复发性皮肤溃疡的罕见病因。

Cutaneous lymphomatoid granulomatosis: a rare cause of recurrent skin ulceration.

作者信息

Wood M L, Harrington C I, Slater D N, Rooney N, Clark A

出版信息

Br J Dermatol. 1984 May;110(5):619-25. doi: 10.1111/j.1365-2133.1984.tb04688.x.

DOI:10.1111/j.1365-2133.1984.tb04688.x

Abstract

We report the case of a 34-year-old male who presented with recurrent skin ulceration due to lymphomatoid granulomatosis. Monoclonal antibody studies showed a high T helper (T4):T suppressor (T8) cell ratio in both the lesions and the peripheral blood. Plasma cells in the infiltrate showed IgA lambda staining but as yet no monoclonal immunoglobulin has been identified in the blood or urine. Lymphocytes bearing markers of immature cells (T10) were observed in the tissue and blood.

摘要

我们报告了一例34岁男性患者，该患者因淋巴瘤样肉芽肿病出现复发性皮肤溃疡。单克隆抗体研究显示，病变部位和外周血中的辅助性T细胞（T4）与抑制性T细胞（T8）比例均较高。浸润中的浆细胞显示IgA λ染色，但血液或尿液中尚未鉴定出单克隆免疫球蛋白。在组织和血液中观察到带有未成熟细胞标志物（T10）的淋巴细胞。