一例选择性IgM缺乏症：同种型特异性抑制性T淋巴细胞。
A case of selective IgM deficiency: isotype-specific suppressor T lymphocytes.
作者信息
Matsushita S, Inoue T, Okubo H
出版信息
Jpn J Med. 1984 May;23(2):149-51. doi: 10.2169/internalmedicine1962.23.149.
Abstract
A case of selective IgM deficiency with giant leiomyoma of the stomach in a 66-year-old male is reported. Peripheral blood mononuclear cells from the patient synthesized only a small amount of IgM in the presence of pokeweed mitogen (PWM) in vitro. Co-culture of counterpart lymphocytes from the patient and a disease-free individual revealed that increased activity of IgM-specific suppressor T lymphocytes led to a IgM deficiency in this case.
摘要
报告了一例66岁男性患选择性IgM缺乏症并伴有胃巨大平滑肌瘤的病例。患者的外周血单个核细胞在体外有商陆有丝分裂原（PWM）存在的情况下仅合成少量IgM。患者与一名无病个体的对应淋巴细胞共培养显示，IgM特异性抑制性T淋巴细胞活性增加导致了该病例中的IgM缺乏。
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