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大鼠和小鼠中产生IgA细胞的存在与微生物状态的关系。

Presence of IgA-producing cells in rats and mice in relation to microbial status.

作者信息

Mullink J W, Morsink F H

出版信息

Lab Anim. 1984 Jul;18(3):252-7. doi: 10.1258/002367784780958196.

DOI:10.1258/002367784780958196
PMID:6235399
Abstract

The numbers of IgA-producing cells in intestinal mucosa, mesenteric lymph nodes, lungs and bronchial lymph nodes were scored in rats and mice. A statistically significant difference in the scores existed between germ-free and SPF mice and between gnotobiotic and SPF rats. In a group of SPF rats a statistically significant difference in the scores was demonstrated in relation to several bacterial and viral agents.

摘要

对大鼠和小鼠的肠道黏膜、肠系膜淋巴结、肺和支气管淋巴结中产生IgA的细胞数量进行了评分。无菌小鼠和无特定病原体(SPF)小鼠之间以及悉生动物和SPF大鼠之间的评分存在统计学上的显著差异。在一组SPF大鼠中,与几种细菌和病毒因子相关的评分显示出统计学上的显著差异。

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