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泥螈视网膜中的能量代谢酶。

Enzymes of energy metabolism in the mudpuppy retina.

作者信息

Dick E

出版信息

J Neurochem. 1984 Oct;43(4):1124-31. doi: 10.1111/j.1471-4159.1984.tb12852.x.

DOI:10.1111/j.1471-4159.1984.tb12852.x
PMID:6236283
Abstract

The distributions of glycogen phosphorylase, hexokinase, phosphofructokinase, lactate dehydrogenase, glucose-6-phosphate dehydrogenase, citrate synthase, malate dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, and adenylokinase were determined in the mudpuppy retina. Distinct differences were found in regard to the glycolytic and oxidative capacities of the various layers. In the outer retina, citric acid cycle enzymes were high while glycolytic enzymes were low. Synaptic zones were distinctly enriched in all energy-producing enzymes. Mudpuppy photoreceptors were found to be rich in phosphorylase but poor in glucose-6-phosphate dehydrogenase, suggestive of some evolutionary divergence from mammals in the metabolic machinery which is used to support the visual process.

摘要

测定了泥螈视网膜中糖原磷酸化酶、己糖激酶、磷酸果糖激酶、乳酸脱氢酶、葡萄糖-6-磷酸脱氢酶、柠檬酸合酶、苹果酸脱氢酶、β-羟酰基辅酶A脱氢酶和腺苷酸激酶的分布。发现各层在糖酵解和氧化能力方面存在明显差异。在外层视网膜中,柠檬酸循环酶含量高而糖酵解酶含量低。突触区所有产能量的酶都明显富集。发现泥螈光感受器富含磷酸化酶,但葡萄糖-6-磷酸脱氢酶含量低,这表明在支持视觉过程的代谢机制方面,与哺乳动物存在一些进化差异。

相似文献

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Enzymes of energy metabolism in the mudpuppy retina.泥螈视网膜中的能量代谢酶。
J Neurochem. 1984 Oct;43(4):1124-31. doi: 10.1111/j.1471-4159.1984.tb12852.x.
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Biochem J. 1988 Sep 1;254(2):359-65. doi: 10.1042/bj2540359.
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