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人类胶质瘤中与能量代谢相关的酶

Enzymes related to energy metabolism in human gliomas.

作者信息

Marzatico F, Curti D, Dagani F, Silvani V, Gaetani P, Butti G, Knerich R

出版信息

J Neurosurg Sci. 1986 Jul-Sep;30(3):129-32.

PMID:2946816
Abstract

The evaluation of the specific activity of some enzymes related to energy transduction was performed in 7 fresh samples of malignant gliomas and in 4 samples of normal brain tissue. Compared with normal brain tissue, the hexokinase, phosphofructokinase and citrate synthase activities are lower; the lactate dehydrogenase and succinate dehydrogenase are unchanged, while glucose-6-phosphate dehydrogenase and NADP+-isocitrate dehydrogenase activities are higher in gliomas.

摘要

对7份新鲜恶性胶质瘤样本和4份正常脑组织样本进行了与能量转导相关的一些酶的比活性评估。与正常脑组织相比,胶质瘤中的己糖激酶、磷酸果糖激酶和柠檬酸合酶活性较低;乳酸脱氢酶和琥珀酸脱氢酶活性不变,而葡萄糖-6-磷酸脱氢酶和NADP⁺-异柠檬酸脱氢酶活性较高。

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Neuronal-astrocyte metabolic interactions: understanding the transition into abnormal astrocytoma metabolism.神经元-星形胶质细胞代谢相互作用:了解异常星形细胞瘤代谢的转变。
J Neuropathol Exp Neurol. 2011 Mar;70(3):167-76. doi: 10.1097/NEN.0b013e31820e1152.
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Metabolic patterns in meningiomas.脑膜瘤的代谢模式
J Neurooncol. 2003 Nov;65(2):119-23. doi: 10.1023/b:neon.0000003680.84840.52.
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Purine and pyrimidine metabolism in human gliomas: relation to chromosomal aberrations.人类神经胶质瘤中的嘌呤和嘧啶代谢:与染色体畸变的关系。
Br J Cancer. 1994 Aug;70(2):212-8. doi: 10.1038/bjc.1994.282.
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Metabolic patterns in malignant gliomas.恶性胶质瘤中的代谢模式。
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