Marzatico F, Curti D, Dagani F, Silvani V, Gaetani P, Butti G, Knerich R
J Neurosurg Sci. 1986 Jul-Sep;30(3):129-32.
The evaluation of the specific activity of some enzymes related to energy transduction was performed in 7 fresh samples of malignant gliomas and in 4 samples of normal brain tissue. Compared with normal brain tissue, the hexokinase, phosphofructokinase and citrate synthase activities are lower; the lactate dehydrogenase and succinate dehydrogenase are unchanged, while glucose-6-phosphate dehydrogenase and NADP+-isocitrate dehydrogenase activities are higher in gliomas.
对7份新鲜恶性胶质瘤样本和4份正常脑组织样本进行了与能量转导相关的一些酶的比活性评估。与正常脑组织相比,胶质瘤中的己糖激酶、磷酸果糖激酶和柠檬酸合酶活性较低;乳酸脱氢酶和琥珀酸脱氢酶活性不变,而葡萄糖-6-磷酸脱氢酶和NADP⁺-异柠檬酸脱氢酶活性较高。