Chatterjee S, Bhattacharya S
Toxicol Lett. 1984 Aug;22(2):187-98. doi: 10.1016/0378-4274(84)90065-1.
The interrelationship of reduced glutathione (GSH) and glutathione-S-transferase in the liver of a freshwater climbing perch Anabas testudineus (Bloch) exposed to common industrial pollutants has been studied. In both short- and long-term treatments there was a concomitant decrease in reduced glutathione profile and an increase in glutathione-S-transferase activity. It may be surmised that the majority of xenobiotics of industrial origin are detoxicated by the glutathione glutathione-S-transferase pathways enabling the fish to survive exposure to the additive and/or synergistic toxicity of mixtures of poisons.
研究了暴露于常见工业污染物的淡水攀鲈龟壳攀鲈（Anabas testudineus，布洛赫）肝脏中还原型谷胱甘肽（GSH）与谷胱甘肽-S-转移酶的相互关系。在短期和长期处理中，还原型谷胱甘肽水平均随之下降，而谷胱甘肽-S-转移酶活性则增加。可以推测，大多数工业来源的外源性物质通过谷胱甘肽-谷胱甘肽-S-转移酶途径解毒，使鱼类能够在接触毒物混合物的相加和/或协同毒性后存活下来。
