果糖-2,6-二磷酸是碳水化合物代谢的一种有效调节剂，它能抑制原生生物纤细裸藻中的海藻糖磷酸化酶。
Fructose 2,6-bisphosphate, a potent regulator of carbohydrate metabolism, inhibits trehalose phosphorylase from protist Euglena gracilis.
作者信息
Miyatake K, Kuramoto Y, Kitaoka S
出版信息
Biochem Biophys Res Commun. 1984 Aug 16;122(3):906-11. doi: 10.1016/0006-291x(84)91176-8.
PMID:6236810
Abstract
Partially purified trehalose phosphorylase (EC 2.4.1.64) from Euglena gracilis SM-ZK was inhibited by fructose 2,6-bisphosphate in both synthetic and degradative directions. Ki value for trehalose phosphorolysis was 1.2 microM and that for trehalose synthesis was 0.5 microM. Functions of fructose 2,6-bisphosphate in Euglena, particularly in the regulative mechanism of the two reserve carbohydrates, paramylon and trehalose, are discussed.
摘要
来自纤细裸藻SM-ZK的部分纯化的海藻糖磷酸化酶（EC 2.4.1.64）在合成和降解方向均受到2,6-二磷酸果糖的抑制。海藻糖磷酸解的Ki值为1.2微摩尔，海藻糖合成的Ki值为0.5微摩尔。本文讨论了2,6-二磷酸果糖在裸藻中的作用，特别是在两种储备碳水化合物——副淀粉和海藻糖的调节机制中的作用。
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