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下肢动脉经皮腔内血管成形术:5年随访

Percutaneous transluminal angioplasty of the arteries of the lower limbs: a 5 year follow-up.

作者信息

Gallino A, Mahler F, Probst P, Nachbur B

出版信息

Circulation. 1984 Oct;70(4):619-23. doi: 10.1161/01.cir.70.4.619.

Abstract

A total of 482 percutaneous transluminal angioplasties (PTAs) of the arteries of the lower limbs were performed in 411 patients between 1977 and 1983. The 5 year patency rate, calculated by the life table method, was 83% for iliac and 58% for femoropopliteal PTA. Clinical improvement after the procedure was confirmed by a significant drop of the arm-ankle pressure difference: 48 +/- 5 mm Hg before vs 17 +/- 5 mm Hg 2 years after iliac PTA (p less than .01) and 73 +/- 5 mm Hg before vs 28 +/- 6 mm Hg after femoropopliteal PTA (p less than .01). The majority of reocclusions occurred within the first year after angioplasty. Patients with stenoses or occlusions of less than 3 cm had a favorable long-term patency rate of 74%. Conversely, patients with femoropopliteal occlusions presenting with pain at rest, diabetes, occlusions of greater than 3 cm, or poor distal runoff had an elevated rate of reocclusion. Complications, which occurred in 8% of the patients in whom PTA was attempted, included local hemorrhage, dissection, embolism, and spasm necessitating surgical intervention in 2%. No deaths or amputations were a direct consequence of PTA. PTA of arteries of the lower limbs may thus be regarded as a valid complementary treatment to vascular surgery in patients with occlusive disease of the peripheral arteries.

摘要

1977年至1983年间,对411例患者的下肢动脉共进行了482次经皮腔内血管成形术(PTA)。采用寿命表法计算,髂动脉PTA的5年通畅率为83%,股腘动脉PTA的5年通畅率为58%。术后临床症状改善表现为臂踝压差显著下降:髂动脉PTA术前为48±5 mmHg,术后2年为17±5 mmHg(p<0.01);股腘动脉PTA术前为73±5 mmHg,术后为28±6 mmHg(p<0.01)。大多数再闭塞发生在血管成形术后的第一年内。狭窄或闭塞长度小于3 cm的患者长期通畅率良好,为74%。相反,伴有静息痛、糖尿病、闭塞长度大于3 cm或远端血流不佳的股腘动脉闭塞患者再闭塞率较高。在尝试进行PTA的患者中,8%发生了并发症,包括局部出血、夹层、栓塞和痉挛,其中2%需要手术干预。没有死亡或截肢是PTA的直接后果。因此,下肢动脉PTA可被视为外周动脉闭塞性疾病患者血管手术的有效补充治疗方法。

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