Salva P, Morer F, Ordoñez J, Rodriguez J
Int J Clin Pharmacol Res. 1983;3(2):129-35.
The effect of two combinations, reverse sequential and monophasic, with cyproterone-acetate, have been studied in a group of 14 women suffering from idiopathic hirsutism. The results obtained prove that both combinations have ovulation blocking properties, by decreasing the FSH, LH, progesterone and oestrogen levels, but also have favourable effects in the treatment of hirsutism. The reverse sequential combination showed an increase in the prolactin figures, although these figures were within normal limits.
对14名患有特发性多毛症的女性组成的一组人群,研究了醋酸环丙孕酮的两种组合(反向序贯组合和单相组合)的效果。所获得的结果证明,两种组合均具有抑制排卵的特性,可降低促卵泡激素(FSH)、促黄体生成素(LH)、孕酮和雌激素水平,但对多毛症的治疗也有良好效果。反向序贯组合的催乳素数值有所增加,尽管这些数值仍在正常范围内。