Melega C, Biscontin S, Mimmi P, Razzani D, Ferraretti A P, Flamigni C
Acta Eur Fertil. 1984 May-Jun;15(3):195-7.
33 infertile women with normal ovulatory cycles were investigated for the presence of a Luteinized Unruptured Follicle Syndrome (L.U.F.) using steroid hormone assays in peritoneal fluid and laparoscopic visualization of ovulation stigmata. We failed to identify a stigma in 36% (12) of the patients in the early luteal phase, 1 subject had a cystic corpus luteum and in 4 cases no diagnosis was made due to the presence of adhesions. The mean hormone concentrations in PF were significantly higher when the stigma was present (17-beta-estradiol, P less than 0,05; progesterone, P less than 0,01; 17-oh-progesterone, P less than 0,05). The two groups (with and without ovulation stigmata) showed no differences in plasma levels of Estradiol (E2) and Progesterone (P). Stigmata were detected only in 17% of subjects with concomitant endometriosis. 3 patients with a luteal phase defect showed low levels of steroids in PF in spite of the presence of an ovulation stigma.
对33名排卵周期正常的不孕女性进行了研究，采用腹腔液类固醇激素检测和腹腔镜观察排卵点，以确定是否存在黄素化未破裂卵泡综合征（L.U.F.）。在黄体早期，我们未能在36%（12例）的患者中发现排卵点，1例患者有囊性黄体，4例因存在粘连而未做出诊断。当存在排卵点时，腹腔液中的平均激素浓度显著更高（17-β-雌二醇，P<0.05；孕酮，P<0.01；17-羟基孕酮，P<0.05）。两组（有和没有排卵点）的雌二醇（E2）和孕酮（P）血浆水平无差异。仅在17%伴有子宫内膜异位症的受试者中检测到排卵点。3例黄体期缺陷患者尽管存在排卵点，但腹腔液中的类固醇水平较低。
