Donnez J, Langerock S, Thomas K
Gynecol Obstet Invest. 1983;16(4):210-20. doi: 10.1159/000299260.
Data on the presence of an ovulation ostium and the volume and the concentrations of estradiol (17 beta-estradiol) and progesterone In women with endometriosis (n = 80) and women with luteinized unruptured follicle (LUF) syndrome (n = 32) are reported and compared with data obtained from normal ovulatory women, previously reported. in women with endometriosis, less ovulation ostia were observed, the difference being significant in moderate and severe endometriosis. During the luteal phase, no statistical difference was found in the amount of peritoneal fluid of women with endometriosis. Estradiol and progesterone levels in the peritoneal fluid of normal women and women with mild endometriosis were not significantly different. Lower steroid concentrations found in peritoneal fluid of women with moderate (phase days 20-22) and severe endometriosis (phase days 14-19 and 20-22) may explain the high incidence of infertility reported in these women (peritoneal steroids deficiency). During the phases days 14-19 and 20-22, very low peritoneal steroid concentrations were found in women with LUF syndrome. It is suggested that progesterone assay in peritoneal fluid is an aid to diagnose the luteinized unruptured syndrome.
报告了子宫内膜异位症患者（n = 80）和黄素化未破裂卵泡（LUF）综合征患者（n = 32）的排卵口存在情况、雌二醇（17β-雌二醇）和孕酮的体积及浓度数据，并与先前报道的正常排卵女性的数据进行了比较。在子宫内膜异位症患者中，观察到的排卵口较少，中度和重度子宫内膜异位症的差异具有统计学意义。在黄体期，子宫内膜异位症患者的腹水量未发现统计学差异。正常女性和轻度子宫内膜异位症女性腹水中的雌二醇和孕酮水平无显著差异。中度（第20 - 22天）和重度子宫内膜异位症患者（第14 - 19天和第20 - 22天）腹水中的类固醇浓度较低，这可能解释了这些患者中报道的高不孕发生率（腹膜类固醇缺乏）。在第14 - 19天和第20 - 22天，LUF综合征患者的腹膜类固醇浓度非常低。建议检测腹水中的孕酮有助于诊断黄素化未破裂综合征。
