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经导管治疗肺动脉狭窄和主动脉缩窄:经皮球囊扩张术的经验

Transcatheter treatment of pulmonary stenosis and coarctation of the aorta: experience with percutaneous balloon dilatation.

作者信息

Rao P S

出版信息

Br Heart J. 1986 Sep;56(3):250-8. doi: 10.1136/hrt.56.3.250.

Abstract

Twenty two children (age range 4 months-20 years) with pulmonary valve stenosis and ten children (age range 1 month-11 years) with coarctation of the aorta underwent balloon dilatation in the 29 month period between October 1983 and February 1986. Number 5-9 French catheters with 5-20 mm balloons were used according to the size of the angiographically measured pulmonary valve annulus or coarcted segment and the aorta proximal to coarctation. The peak inflation pressure used in the balloons varied from 2-5 atm (202-505 kN/m2) for pulmonary valve stenosis and 4-8 atm (404-808 kN/m2) for coarctation, and inflation lasted 8-15 s. At least four balloon dilatations were performed in every case. After balloon dilatation the mean (SD) peak systolic pressure gradient across the pulmonary valve fell from 98 (39) to 33 (13) mm Hg. The cardiac index did not change. After balloon dilatation of aortic coarctation the systolic pressure in the descending aorta rose from 86.4 (17.7) to 107.8 (20) mm Hg and the peak systolic pressure difference across the coarctation fell from 44.1 (19.1) to 8.5 (8.5) mm Hg. The diameter of the angiographically measured coarcted segment increased, the Doppler estimate of the pressure difference across the coarctation decreased, and the femoral pulses improved. There were no important complications. Long term follow up results for balloon dilatation of pulmonary valve stenosis were excellent. Similar follow up was not available for patients after dilatation of aortic coarctation. Percutaneous balloon dilatation for pulmonary stenosis and coarctation of the aorta is a safe and effective alternative to operation. It is the treatment of choice for pulmonary valve stenosis and it may become so for coarctation of the aorta in young children if long term results are favourable.

摘要

在1983年10月至1986年2月的29个月期间,22名患有肺动脉瓣狭窄的儿童(年龄范围4个月至20岁)和10名患有主动脉缩窄的儿童(年龄范围1个月至11岁)接受了球囊扩张术。根据血管造影测量的肺动脉瓣环或缩窄段以及缩窄近端主动脉的大小,使用5-9法国导管及5-20毫米的球囊。肺动脉瓣狭窄球囊的峰值充盈压力为2-5个大气压(202-505千牛/平方米),主动脉缩窄为4-8个大气压(404-808千牛/平方米),充盈持续8-15秒。每例至少进行4次球囊扩张。球囊扩张后,肺动脉瓣跨瓣平均(标准差)收缩压峰值梯度从98(39)毫米汞柱降至33(13)毫米汞柱。心脏指数未改变。主动脉缩窄球囊扩张后,降主动脉收缩压从86.4(17.7)毫米汞柱升至107.8(20)毫米汞柱,缩窄处跨缩窄段的收缩压峰值差从44.1(19.1)毫米汞柱降至8.5(8.5)毫米汞柱。血管造影测量的缩窄段直径增加,缩窄处压差的多普勒估计值降低,股动脉搏动改善。无重要并发症。肺动脉瓣狭窄球囊扩张的长期随访结果良好。主动脉缩窄扩张术后患者尚无类似的随访结果。经皮球囊扩张治疗肺动脉狭窄和主动脉缩窄是一种安全有效的手术替代方法。它是肺动脉瓣狭窄的首选治疗方法,如果长期结果良好,对于幼儿主动脉缩窄也可能成为首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/1236850/262a9fda739f/brheartj00105-0059-a.jpg

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