Thomas P, Allal J, Bontoux D, Rossi F, Poupet J Y, Petitalot J P, Becq-Giraudon B
Ann Rheum Dis. 1984 Oct;43(5):716-20. doi: 10.1136/ard.43.5.716.
A retrospective study showed musculoskeletal manifestations in 32 of 108 patients treated for infective endocarditis in several departments at the Poitiers CHU. Such manifestations included articular pain or aseptic arthritis, typically involving the major joints, as well as vertebral osteomyelitis, low back pain (inflammatory or non-inflammatory), and myalgia. Patients showing such signs were generally younger than those without musculoskeletal involvement, diagnosis was made later, and prognosis was worse; streptococcus D was more often involved, and microscopic haematuria was more common. With the exception of vertebral osteomyelitis, the pathogenesis was not clear.
一项回顾性研究显示，在普瓦捷大学中心医院几个科室接受感染性心内膜炎治疗的108例患者中，有32例出现了肌肉骨骼表现。这些表现包括关节疼痛或无菌性关节炎，通常累及大关节，以及脊椎骨髓炎、腰痛（炎性或非炎性）和肌痛。出现这些症状的患者通常比没有肌肉骨骼受累的患者年轻，诊断较晚，预后较差；D组链球菌感染更为常见，镜下血尿也更普遍。除脊椎骨髓炎外，发病机制尚不清楚。
