粗糙脉孢菌对氨基酸利用的氮调节
Nitrogen regulation of amino acid utilization by Neurospora crassa.
作者信息
DeBusk R M, Ogilvie S
出版信息
J Bacteriol. 1984 Nov;160(2):493-8. doi: 10.1128/jb.160.2.493-498.1984.
Abstract
The production of an extracellular deaminase activity involved with the utilization of amino acids as sole sources of nitrogen is under the control of the nit-2 locus of Neurospora crassa. This locus is the sole major nitrogen regulatory locus described for N. crassa and is believed to encode a positive effector required for induction of activities involved with the utilization of alternate nitrogen sources. Production of deaminase activity requires the lifting of nitrogen metabolite repression, the presence of a functional nit-2 gene product, and specific induction by amino acids. Additional parameters of enzyme production are described.
摘要
与将氨基酸作为唯一氮源利用相关的细胞外脱氨酶活性的产生，受粗糙脉孢菌nit-2基因座的控制。该基因座是已描述的粗糙脉孢菌唯一主要的氮调节基因座，据信它编码一种诱导与利用替代氮源相关活性所需的正效应物。脱氨酶活性的产生需要解除氮代谢物阻遏、存在功能性的nit-2基因产物以及氨基酸的特异性诱导。文中还描述了酶产生的其他参数。
相似文献
1
Nitrogen regulation of amino acid utilization by Neurospora crassa.粗糙脉孢菌对氨基酸利用的氮调节
J Bacteriol. 1984 Nov;160(2):493-8. doi: 10.1128/jb.160.2.493-498.1984.
2
Nitrogen regulation of amino acid catabolism in Neurospora crassa.粗糙脉孢菌中氨基酸分解代谢的氮调节
Biochem Genet. 1978 Apr;16(3-4):343-54. doi: 10.1007/BF00484090.
3
Participation of an extracellular deaminase in amino acid utilization by Neurospora crassa.一种细胞外脱氨酶在粗糙脉孢菌氨基酸利用中的作用。
J Bacteriol. 1984 Aug;159(2):583-9. doi: 10.1128/jb.159.2.583-589.1984.
4
Regulation of amino acid utilization in Neurospora crassa: effect of nmr-1 and ms-5 mutations.粗糙脉孢菌中氨基酸利用的调控：nmr-1和ms-5突变的影响
J Bacteriol. 1984 Nov;160(2):656-61. doi: 10.1128/jb.160.2.656-661.1984.
5
Amber nonsense mutations in regulatory and structural genes of the nitrogen control circuit of Neurospora crassa.粗糙脉孢菌氮控制回路调节基因和结构基因中的琥珀色无义突变。
Curr Genet. 1986;10(9):677-84. doi: 10.1007/BF00410916.
6
Physiological adaptation to the loss of amino acid transport ability.对氨基酸转运能力丧失的生理适应。
J Bacteriol. 1982 Oct;152(1):545-8. doi: 10.1128/jb.152.1.545-548.1982.
7
Molecular cloning of nit-2, a regulatory gene required for nitrogen metabolite repression in Neurospora crassa.粗糙脉孢菌中氮代谢物阻遏所需调控基因nit-2的分子克隆。
Gene. 1986;46(2-3):291-5. doi: 10.1016/0378-1119(86)90414-2.
8
Xanthine dehydrogenase expression in Neurospora crassa does not require a functional nit-2 regulatory gene.粗糙脉孢菌中黄嘌呤脱氢酶的表达不需要功能性的nit-2调控基因。
Biochem Genet. 1988 Feb;26(1-2):37-52. doi: 10.1007/BF00555487.
9
10
引用本文的文献
1
Exploring regulation genes involved in the expression of L-amino acid oxidase in Pseudoalteromonas sp. Rf-1.探索参与假交替单胞菌Rf-1中L-氨基酸氧化酶表达的调控基因。
PLoS One. 2015 Mar 27;10(3):e0122741. doi: 10.1371/journal.pone.0122741. eCollection 2015.
2
Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis.含GATA的DNA及定点诱变对转录阻遏物NmrA配体结合特性的调控
Protein Sci. 2004 Dec;13(12):3127-38. doi: 10.1110/ps.04958904. Epub 2004 Nov 10.
3
Regulation of amino acid utilization in Neurospora crassa: effect of nmr-1 and ms-5 mutations.粗糙脉孢菌中氨基酸利用的调控：nmr-1和ms-5突变的影响
J Bacteriol. 1984 Nov;160(2):656-61. doi: 10.1128/jb.160.2.656-661.1984.
本文引用的文献
1
Characterization of 2-aminoisobutyric acid transport in Neurospora crassa: a general amino acid permease-specific substrate.粗糙脉孢菌中2-氨基异丁酸转运的特性：一种通用氨基酸通透酶特异性底物。
J Bacteriol. 1981 Sep;147(3):944-8. doi: 10.1128/jb.147.3.944-948.1981.
2
Alternate mechanism for amino acid entry into Neurospora crassa: extracellular deamination and subsequent keto acid transport.氨基酸进入粗糙脉孢菌的另一种机制：细胞外脱氨基作用及随后的酮酸转运。
J Bacteriol. 1981 Apr;146(1):163-9. doi: 10.1128/jb.146.1.163-169.1981.
3
Physiological and regulatory properties of the general amino acid transport system of Neurospora crassa.粗糙脉孢菌一般氨基酸转运系统的生理和调节特性。
J Bacteriol. 1980 Jul;143(1):188-97. doi: 10.1128/jb.143.1.188-197.1980.
4
Demonstration of de novo synthesis of Neurospora crassa nitrate reductase during induction.诱导过程中粗糙脉孢菌硝酸还原酶从头合成的证明。
J Biol Chem. 1980 Jan 25;255(2):690-3.
5
Participation of an extracellular deaminase in amino acid utilization by Neurospora crassa.一种细胞外脱氨酶在粗糙脉孢菌氨基酸利用中的作用。
J Bacteriol. 1984 Aug;159(2):583-9. doi: 10.1128/jb.159.2.583-589.1984.
6
Physiological adaptation to the loss of amino acid transport ability.对氨基酸转运能力丧失的生理适应。
J Bacteriol. 1982 Oct;152(1):545-8. doi: 10.1128/jb.152.1.545-548.1982.
7
Nitrogen regulation of acid phosphatase in Neurospora crassa.粗糙脉孢菌中酸性磷酸酶的氮调节
J Bacteriol. 1980 Mar;141(3):1470-3. doi: 10.1128/jb.141.3.1470-1473.1980.
8
Genetic control of nitrogen assimilation in bacteria.细菌中氮同化的遗传控制
Annu Rev Genet. 1982;16:135-68. doi: 10.1146/annurev.ge.16.120182.001031.
9
Regulation of L-amino acid oxidase and of D-amino acid oxidase in Neurospora crassa.粗糙脉孢菌中L-氨基酸氧化酶和D-氨基酸氧化酶的调控
Mol Gen Genet. 1982;186(1):33-9. doi: 10.1007/BF00422908.
10
Regulation of nitrogen metabolism and gene expression in fungi.真菌中氮代谢与基因表达的调控
Microbiol Rev. 1981 Sep;45(3):437-61. doi: 10.1128/mr.45.3.437-461.1981.
Zotero 插件