Ogilvie-Villa S, DeBusk R M, DeBusk A G
J Bacteriol. 1981 Sep;147(3):944-8. doi: 10.1128/jb.147.3.944-948.1981.
We report the characterization of an amino acid 2-aminoisobutyric acid was transported solely by the general amino acid permease and not by the neutral amino acid permease. Furthermore, this substrate was not metabolized after transport. The potential for a system-specific nonmetabolizable substrate as a tool in the analysis of amino acid transport and its regulation is discussed.
我们报告了对一种氨基酸——2-氨基异丁酸的特性描述,它仅通过一般氨基酸通透酶转运,而不通过中性氨基酸通透酶转运。此外,这种底物在转运后不会被代谢。本文还讨论了使用系统特异性不可代谢底物作为分析氨基酸转运及其调控工具的潜力。