Anagnostou A, Schade S, Barone J, Fried W
Blood. 1978 Mar;51(3):549-53.
The production of erythropoietin by rats fed a protein-deficient diet is markedly decreased. This defect can be rapidly reversed by feeding protein. In the reported experiments we investigated the effect of protein deficiency on the extra-renal production of erythropoietin. The results indicate that the production of erythropoietin in nephrectomized animals is insensitive to protein depletion.
喂食蛋白质缺乏饮食的大鼠促红细胞生成素的产生显著减少。通过喂食蛋白质,这种缺陷可迅速逆转。在报告的实验中,我们研究了蛋白质缺乏对促红细胞生成素肾外产生的影响。结果表明,肾切除动物中促红细胞生成素的产生对蛋白质消耗不敏感。