Coulaud J P
Presse Med. 1984 Oct 13;13(36):2201-5.
Infestation with intestinal parasites can now be controlled by several broad-spectrum compounds. These drugs are particularly useful against multiple intestinal parasites, as frequently found in tropical and subtropical countries, and are well suited to mass treatment. The introduction of oxamniquine and praziquantel constitutes a break through in the treatment of intestinal and urogenital schistosomiasis. Praziquantel also perfectly controls taeniasis, sometimes including its larval form (cysticercosis). Experience is too short to evaluate the effectiveness of benzimidazoles (notably albendazole), administered post-operatively or alone when surgery is contra-indicated, in the treatment of hepatic or alveolar hydatid disease. Better drugs are needed to treat Fasciola hepatica infestation or to control onchocerciasis and other diseases due to filariae.
现在，几种广谱化合物可以控制肠道寄生虫感染。这些药物对多种肠道寄生虫特别有效，在热带和亚热带国家经常发现这些寄生虫，并且非常适合大规模治疗。奥沙尼喹和吡喹酮的引入在肠道和泌尿生殖系统血吸虫病的治疗方面构成了一项突破。吡喹酮还能很好地控制绦虫病，有时包括其幼虫形式（囊尾蚴病）。评估苯并咪唑类药物（特别是阿苯达唑）在肝包虫病或肺泡包虫病治疗中的有效性的经验还不足，这些药物在手术后使用或在手术禁忌时单独使用。治疗肝片吸虫感染或控制盘尾丝虫病及其他丝虫病需要更好的药物。
