Bes M, Brun Y, Fleurette J
Ann Microbiol (Paris). 1984 Sep-Oct;135B(2):165-76.
Coagulase-negative staphylococci, and in particular Staphylococcus epidermidis, are now being recognized as causing human infections with increasing frequency; the absence of an internationally accepted system of phage-typing for coagulase-negative staphylococci led us to isolate new phages. Fifty strains of S. epidermidis isolated from human infections were induced with mitomycin C: eight phages (41, 63, 118-II, 138, 245, 336, 392 and 550) were isolated. These phages were propagated on five different strains of S. epidermidis. Their phages were propagated on five different strains of S. epidermidis. Their lytic activity as studied on 561 strains. Phages 336, 392 and 550 had a different host-range and different propagative strains; they typed 93% of the strains susceptible to the 8 phages. The other phages had an activity similar to that of phage 336. Twenty-one per cent of non-epidemic strains were susceptible to at least one of the three phages. The reproducibility, specificity and discriminatory power of these phages suggest they may be a useful addition to previously recognized phages.
凝固酶阴性葡萄球菌，尤其是表皮葡萄球菌，目前正被越来越频繁地认定为可引发人类感染；由于缺乏国际公认的凝固酶阴性葡萄球菌噬菌体分型系统，我们着手分离新型噬菌体。用丝裂霉素C诱导从人类感染中分离出的50株表皮葡萄球菌：分离出8种噬菌体（41、63、118-II、138、245、336、392和550）。这些噬菌体在5种不同的表皮葡萄球菌菌株上进行增殖。研究了它们在561株菌株上的裂解活性。噬菌体336、392和550具有不同的宿主范围和不同的增殖菌株；它们对8种噬菌体敏感的菌株中的93%进行了分型。其他噬菌体的活性与噬菌体336相似。21%的非流行菌株对这三种噬菌体中的至少一种敏感。这些噬菌体的可重复性、特异性和鉴别能力表明，它们可能是先前公认噬菌体的有益补充。
