胎牛血清和表皮生长因子可在体外阻止一种类抑素生长抑制剂对艾氏腹水乳腺癌细胞的抑制作用。
Fetal calf serum and epidermal growth factor prevent the inhibitory action of a chalone-like growth inhibitor for Ehrlich ascites mammary carcinoma cells in vitro.
作者信息
Lehmann W, Graetz H, Widmayer R, Langen P
出版信息
Biomed Biochim Acta. 1984;43(7):971-4.
PMID:6240265
Abstract
A growth inhibitor for the Ehrlich ascites mammary carcinoma, purified from bovine mammary gland, is antagonized by very low concentrations of epidermal growth factor (2-16 X 10(-10) M) or fetal calf serum (0.001-0.1%). Thus, epidermal growth factor and the compounds in fetal calf serum have the same effect as earlier described for insulin and proinsulin [1-3].
摘要
从牛乳腺中纯化得到的一种艾氏腹水乳腺癌生长抑制剂，会被极低浓度的表皮生长因子（2 - 16×10⁻¹⁰ M）或胎牛血清（0.001 - 0.1%）所拮抗。因此，表皮生长因子和胎牛血清中的化合物具有与之前描述的胰岛素和胰岛素原相同的作用[1 - 3]。
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