• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

囊性纤维化的钙假说。

The calcium hypothesis of cystic fibrosis.

作者信息

Katz S, Schöni M H, Bridges M A

出版信息

Cell Calcium. 1984 Oct;5(5):421-40. doi: 10.1016/0143-4160(84)90021-6.

DOI:10.1016/0143-4160(84)90021-6
PMID:6240316
Abstract

Data have been presented which suggests that various CF cell types show evidence of alterations in calcium homeostasis. The significance of these observations and the exact nature of the putative calcium defect in CF remains to be elucidated. It must also be determined whether this possible defect is primary, or is secondary or tertiary to some more basic lesion. The data reviewed suggests that altered calcium homeostasis may play some focal role in the aetiology or the pathogenesis of CF.

摘要

已有数据表明,多种囊性纤维化(CF)细胞类型显示出钙稳态改变的迹象。这些观察结果的意义以及CF中假定的钙缺陷的确切性质仍有待阐明。还必须确定这种可能的缺陷是原发性的,还是继发于或 tertiary 于某些更基本的病变。所回顾的数据表明,改变的钙稳态可能在CF的病因学或发病机制中起某种局部作用。

注

“tertiary”这个词原文有误,推测可能是“secondary”(继发的),按照正确推测翻译如上。

相似文献

1
The calcium hypothesis of cystic fibrosis.囊性纤维化的钙假说。
Cell Calcium. 1984 Oct;5(5):421-40. doi: 10.1016/0143-4160(84)90021-6.
2
Hypothesis revisited: cystic fibrosis: a disturbance of water and electrolyte movement in exocrine secretory tissue associated with altered prostaglandin (PGE2) metabolism?再探假说:囊性纤维化——外分泌分泌组织中与前列腺素(PGE2)代谢改变相关的水和电解质运动紊乱?
J Pediatr Gastroenterol Nutr. 1984;3(1):15-22.
3
Defective regulation of apical membrane chloride transport and exocytosis in cystic fibrosis.囊性纤维化中顶端膜氯离子转运和胞吐作用的调节缺陷。
Biosci Rep. 1988 Feb;8(1):27-33. doi: 10.1007/BF01128969.
4
Calcium and sodium transport processes in patients with cystic fibrosis. I. A specific decrease in Mg2+-dependent, Ca2+-adenosine triphosphatase activity in erythrocyte membranes from cystic fibrosis patients.囊性纤维化患者的钙和钠转运过程。I. 囊性纤维化患者红细胞膜中镁离子依赖性钙三磷酸腺苷酶活性的特异性降低。
Pediatr Res. 1978 Nov;12(11):1033-8. doi: 10.1203/00006450-197811000-00001.
5
Serum amylase isoenzymes in cystic fibrosis patients. Evidence for a generalized defect in exocrine gland secretory regulation.
Pediatr Res. 1980 Nov;14(11):1168-72. doi: 10.1203/00006450-198011000-00004.
6
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.在囊性纤维化中,跨人类气管腺培养物的液体转运发生改变。
J Physiol. 1997 Jun 15;501 ( Pt 3)(Pt 3):637-47. doi: 10.1111/j.1469-7793.1997.637bm.x.
7
The molecular and biochemical basis of cystic fibrosis.囊性纤维化的分子与生化基础。
Biosci Rep. 1987 Mar;7(3):167-85. doi: 10.1007/BF01124787.
8
Cystic fibrosis--a problem of permeability?
Pediatrics. 1971 Nov;48(5):693-4.
9
Calcium and cystic fibrosis.钙与囊性纤维化
Scan Electron Microsc. 1986(Pt 1):165-78.
10
The biochemical defect in cystic fibrosis.囊性纤维化的生化缺陷。
Clin Sci (Lond). 1988 Apr;74(4):337-45. doi: 10.1042/cs0740337.

引用本文的文献

1
The Role of Specialized Pro-Resolving Mediators in Cystic Fibrosis Airways Disease.特殊促消退介质在囊性纤维化气道疾病中的作用
Front Pharmacol. 2020 Sep 2;11:1290. doi: 10.3389/fphar.2020.01290. eCollection 2020.
2
Recent advances in cystic fibrosis.囊性纤维化的最新进展
J Inherit Metab Dis. 1988;11 Suppl 1:94-109. doi: 10.1007/BF01800575.
3
Pseudomonas aeruginosa variants isolated from patients with cystic fibrosis are killed by a bactericidal protein from human polymorphonuclear leukocytes.从囊性纤维化患者体内分离出的铜绿假单胞菌变体可被人类多形核白细胞产生的一种杀菌蛋白杀死。
Infect Immun. 1991 Jun;59(6):2152-7. doi: 10.1128/iai.59.6.2152-2157.1991.