无系统性红斑狼疮患者血清中的抗双链DNA抗体。
Anti-dsDNA antibodies in sera of patients without systemic lupus erythematosus.
作者信息
Wollina U
出版信息
Allerg Immunol (Leipz). 1984;30(4):222-4.
PMID:6240935
Abstract
133 sera of patients without systemic lupus erythematosus (SLE) have been analyzed by an ultramicro ELISA for antibodies to dsDNA. 14 sera (10.5%) had antibody concentrations greater than 120 mU/ml ("positive"). Additionally, 29 sera (21.5%) had antibodies within the range 60 . . . 120 mU/ml ("borderline"). Pathogenetic significance is discussed briefly.
摘要
采用超微量酶联免疫吸附测定法（ultramicro ELISA）对133份无系统性红斑狼疮（SLE）患者的血清进行了双链DNA抗体分析。14份血清（10.5%）的抗体浓度大于120 mU/ml（“阳性”）。此外，29份血清（21.5%）的抗体浓度在60……120 mU/ml范围内（“临界值”）。简要讨论了其发病机制意义。
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