Schwartz G F, Patchefsky A S, Feig S A, Shaber G S, Schwartz A B
Ann Surg. 1980 Jan;191(1):8-12. doi: 10.1097/00000658-198001000-00002.
Two hundred thirty-two biopsies have been performed for nonpalpable mammary lesions, detectable by mammography, but not clinically apparent. Sixty-two malignancies were demonstrated within this group, including thirty invasive ductal cancers, seven minimally invasive ductal cancers, 20 noninvasive ductal cancers, and five lobular carcinomas-in situ. When mastectomy specimens were examined for evidence of multifocal cancer in quadrants other than that in which the primary was located, 39.6% of the breasts examined demonstrated evidence of multifocal cancer ductal or lobular, invasive or non-invasive. These findings suggest that any therapeutic procedure for invasive or noninvasive ductal cancer which does not include total mastectomy may leave behind foci of cancer which may be a threat to the patient.
对232例乳腺X线检查可发现但临床未触及的乳腺病变进行了活检。该组中发现62例恶性肿瘤，包括30例浸润性导管癌、7例微浸润性导管癌、20例非浸润性导管癌和5例小叶原位癌。当对乳房切除术标本进行检查，以寻找原发灶所在象限以外其他象限多灶性癌的证据时，39.6%的受检乳房显示存在导管或小叶多灶性癌，包括浸润性或非浸润性。这些发现表明，任何不包括全乳房切除术的浸润性或非浸润性导管癌治疗方法，都可能遗留癌灶，这可能对患者构成威胁。
