Aflatoxin metabolism and absence of cytochrome P-450 in rat colon tissue during vitamin A malnutrition.
作者信息
Adekunle A A, Campbell T C, Campbell S C
出版信息
Experientia. 1978 Feb 15;34(2):230-2. doi: 10.1007/BF01944697.
PMID:624362
Abstract
Homogenized mucosal linings prepared from vitamin A adequate and deficient male rats were used in metabolic studies of aflatoxin B1 (AFB1). Cytochrome P-420 was identified in both groups which metabolized AFB1 to 4 metabolic products in vitro. The implications of this observation are discussed in relation to colon carcinoma.
摘要
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