Baker D A, Phillips C A
Obstet Gynecol. 1980 Mar;55(3 Suppl):12S-15S. doi: 10.1097/00006250-198003001-00004.
Evidence is growing that relates maternal coxsackievirus infection to increased neonatal mortality and an increase of congenital anomalies. Four cases of fulminant perinatal coxsackievirus infections that were fatal to the newborns are presented. Coxsackievirus infections in pregnancy are usually either subclinical or produce minimal symptoms in the mother. The cases presented point out the potential severity of coxsackievirus infections in the neonatal period. Prevention of the disease and isolation of infected individuals are the mainstays of therapy.
越来越多的证据表明,孕产妇柯萨奇病毒感染与新生儿死亡率增加及先天性异常增多有关。本文报告了4例暴发性围产期柯萨奇病毒感染导致新生儿死亡的病例。孕期柯萨奇病毒感染通常要么是亚临床的,要么在母亲身上产生轻微症状。所报告的病例指出了柯萨奇病毒感染在新生儿期的潜在严重性。预防该疾病和隔离感染者是主要的治疗方法。