Horrocks J C, De Dombal F T
Gut. 1978 Jan;19(1):19-26. doi: 10.1136/gut.19.1.19.
This paper describes the clinical presentation of 360 patients suffering from "dyspepsia" at the time of their initial visit to two hospitals in Yorkshire. Disease categories studied were cholecystitis, duodenal ulcer, gastric ulcer, gastric cancer, and "functional" dyspepsia, with at least 50 patients in each category. The findings of this series are contrasted with "textbook" descriptions of these conditions. Some contrasts are quite surprising-for example, most of the 360 patients claimed that their pain was not aggravated by food. It is suggested that one reason for diagnostic error in this area of medicine is that clinicians have a faulty mental "database" of information with regard to the presentation of the various diseases concerned.
本文描述了360名在初次就诊于约克郡两家医院时患有“消化不良”的患者的临床表现。所研究的疾病类别包括胆囊炎、十二指肠溃疡、胃溃疡、胃癌以及“功能性”消化不良,每个类别至少有50名患者。本系列研究结果与这些病症的“教科书”描述形成对比。一些对比结果颇为惊人——例如,这360名患者中的大多数声称他们的疼痛不会因进食而加重。有人认为,在医学的这一领域出现诊断错误的一个原因是临床医生对于相关各种疾病的表现有着错误的心理“信息库”。