[Portal hypertension in sarcoidosis. Three cases including one with liver fibrosis and malignant hepatoma with osseous stroma (author's transl)].

The high incidence of hepatic lesions in sarcoidosis contrasts with the extreme rarity of portal hypertension. The mechanism of the latter is as obscure as the pathogeny of the disease. The liver may contain many or very few tuberculoid follicles, and its structure may be normal and non-fibrotic (as in our first two patients) or sclerotic, though rarely cirrhotic. In most cases the spleen is enormous, which raises the problem of portal hypertension by overload. Our third patient seems to be an unique case of progressive change to malignant hepatoma with osseous metaplasia, complicated with cervical metastases.