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DBA和C3H小鼠学习速度的单基因遗传。穿梭箱中的行为遗传学研究。

Monogene inheritance of learning speed in DBA and C3H mice. A behavioral genetic study in the shuttle-box.

作者信息

Buselmaier W, Geiger S, Reichert W

出版信息

Hum Genet. 1978 Jan 19;40(2):209-14. doi: 10.1007/BF00272303.

DOI:10.1007/BF00272303
PMID:624548
Abstract

We carried out investigations on C3H, NMRI, C57Bl/6, Balb/c, Balb/cN, and DBA inbred mouse strains in the shuttle-box to see whether their learning behavior is genetically controlled. The highly different learning behavior of the parental strains made it possible to test the F1 hybrids and the F2 generation. The environmental influences were standardized as much as possible. In particular, influences possible during the lactation period were excluded by using foster breeding. The results enable us to postulate monogenic inheritance for the learning speed in the shuttle-box. The inheritance is interpreted as codominant. The investigations are part of a basic study in mammalian behavior genetics from the human genetic aspect.

摘要

我们在穿梭箱中对C3H、NMRI、C57Bl/6、Balb/c、Balb/cN和DBA近交系小鼠进行了研究,以观察它们的学习行为是否受基因控制。亲本品系高度不同的学习行为使得对F1杂种和F2代进行测试成为可能。环境影响尽可能标准化。特别是,通过代孕繁殖排除了哺乳期可能产生的影响。结果使我们能够假定穿梭箱中学习速度的单基因遗传。这种遗传被解释为共显性。这些研究是从人类遗传学角度对哺乳动物行为遗传学进行的一项基础研究的一部分。

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